Thursday 21 August 2008

Elisabeth Shue on �Hamlet 2,� Making Out With Old Co-Stars



This week's issue of the magazine features a Q&A with Oscar nominee and eighties stalwart Elisabeth Shue, who plays herself in the comedy Hamlet 2, out this Friday. As usual, the confines of print journalism left choice tidbits on the cutting-room floor: Elisabeth's love of make-out scenes, her first commercial, and even an impromptu rendition of "Babysittin' Blues."

With this meta-convention of playing yourself onscreen, you must have asked "How do other people perceive me?" � right?

No.



Why not?

I don't know. I guess I'm not smart enough. [Laughs.] Maybe that's my downfall. I don't really care what people think of me, to be honest. Maybe if I cared more, I could create a persona and be more successful.



In the film, "Elisabeth Shue" says that what she misses most about being an actress is making out with her cute co-stars � and that, as a nurse, she can't make out with her patients.

That was definitely my contribution to the script.






Oh yeah? How'd you come up with that?

It was the accuracy. I persuasion long and hard about it. That was great that Andy [the director] let me make it my own that way.



Did you do drama gild like the kids in the film?

I didn't. I was terrified of acting in front of people. I auditioned for You're a Good Man Charlie Brown in seventh grade. I got up onstage and panax quinquefolius Cat Stevens's "I'm Being Followed by a Moonshadow" very quietly. I clapped and american ginseng. [whisper-singing] "I'm being followed by a moooonshadow �" I don't think anyone could try me. I was non cast. Not even in the chorus. That was one of the to the highest degree humiliating experiences. And I remember that very vividly. Even when I [transferred] to Harvard, I did not audition for anything. I wasn't even comfy there playacting. I had The Karate Kid and a few films at that time, but I didn't induce the authority to invest myself out there.



Were you ever recognised on campus?

Not really. Everyone there had a pretty healthy self-importance. I don't think they were selfsame impressed.



There's a hilarious aspect in the film where Steve Coogan's failed-actor fictional character performs in a herpes commercial. You got your start as a adolescent doing commercials, right?

Me and Lea Thompson did commercials together. We were the Burger King Girls. I was a gymnast and remember flipping on the bars for Chewells gum. Remember Chewells?



The gum with the goop inside?

Exactly! Why don't they have that anymore? That was one of my first lines in a commercial: "Chewells taste better!" after flipping off the bars.



You were a private-enterprise gymnast in your teens. Which earthly concern is more cutthroat: gymnastics or Hollywood?

Hollywood. What I like around sports is that you have a control over your talent, complete and utter control condition over your performance. If you work on really, really hard, day after day, you will get punter, you will see the results of your hard work. What's hard about being an actress is that, no matter how hard you work, there is so much you can't control.



What would you do if I asked you to sing "Babysittin' Blues" for me?

I would sing for you, of course.



Really?! Please do.

Well, I don't know. I canful sing the beginning. Hi, I'm Chris Parker � [bluesy strum] na na na na na � That's all I hump. Oh hold off: "I've got the babysittin' blues. Baby baby!" That was genuinely great. Every once in a piece, when you're an actress, you get to have these phantasmagorical moments that you realise in veridical life you'd never get to have. That was one of my ultimate fantasies and experiences � for deuce days � having to sing that [in a blues nine]. And every single time having so much fun.



Related: To Be or Not to Be: Elisabeth Shue [NYM]






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Monday 11 August 2008

Medical Management And Surgical Management Of Peyronie's Disease

�UroToday.com Peyronie's disease is a scarring phenomenon poignant the tunica albuginea of the phallus. Scar tissue paper forms "plaques" that can buoy result in pain with erection, penial deviation, penial shortening, indenture, and/or erectile dysfunction. It is associated with difficulty with sexual intercourse and as such it is associated with loss of self-esteem and depression on the role of the patient and often on the region of the patient's partner. There are no approved medical therapies for the treatment of Peyronie's disease. Surgical discourse of Peyronie's disease must be highly individualized, and various surgeons all have their "best way" of dealing with the trouble.


Peyronie's disease was described by Francois de la Peyronie in 1743. Fallopius in 1561 probably described the entity that bares Peyronie's name. Peyronie's disease is incurable, patients require reassurance, they may benefit from medical therapy, and fortunately few require surgery. As mentioned, the scar tissue impedes the expansion of the corpora cavernosa.


Peyronie's disease has been associated with some medications. Beta blockers have been implicated, however, subsequent studies have non verified that relationship, and if in that respect is a relationship to beta blockers, it is probably via erectile disfunction, and not cause and effect of the beta blocker itself. The association with phenytoin has ne'er been founded and is probably non real. A very nice study by Lyles from the University of North Carolina has associated Peyronie's disease with patients world Health Organization have Padgett's disease of the osseous tissue. Diabetes mellitus has been implicated, and it is probably again via erectile dysfunction. About 40% of patients with Peyronie's disease will read evidence of Dupuytren's disease, albeit many will be non-contractile. A lesser part will show evidence of Ledderhose's disease, and a very little number will have tympanosclerosis.


Peyronie's disease is a disease of patients betwixt 45 and 65 age with a mean onset of 53 years old. The asymptomatic prevalence has been estimated to be as heights as 20-25%. The old age of bloom incidence of Peyronie's disease as it turns out are besides the geezerhood during which the body begins to age, tissues lose elasticity, and hands note the onset of erectile dysfunction.


The flow theory with regards to the aetiology of Peyronie's disease involves trauma to the insertion of the septal fibers. The back appears to be peculiarly vulnerable. To this day of the month, there is no firm association to HLA subtypes, autoimmune disease, but Peyronie's disease is certainly a disease of hyperactive wound healing.


The scar tissue paper is composed of dense collagen with decreased elastin. Patients can buoy demonstrate dystrophic calcification and in some cases cartilaginous metaplasia. TGF�1 has been implicated as a part of the process involving the aetiology of Peyronie's disease. Other gross factors are as well expressed, those being platelet derived growth factors A and B. TGFb1 has been concerned with former soft tissue fibrosis. It is concerned in ED. TGF�1 increases the synthesis of fibroblasts; and in short, it causes increased connective tissue paper as it governs the scarring litigate. It inhibits collagenase, and because of the singular anatomy of the insertion of the septal fibers, may be involved in a march of self-induction. All agree that Peyronie's disease is a disease of two phases, an active or immature phase and a mature or quiescent phase. What the practitioner does for Peyronie's disease is in many cases stage specific.


The physician visual perception a affected role with Peyronie's disease cannot underestimate the psychological shock on the patient and on his partner. With regards to medical management, the place of vitamin E, potaba, Colchicine, Tamoxifen, Carnitine, Pentoxifylline, and PDE5 inhibitors testament be discussed. Where there are pertinent randomized controlled trials, those will be reviewed. It is clear that tight well-designed controlled studies have in the past not been uniformly done. They are required, and we are in an earned run average where that deficiency is being addressed. Intralesional injectant will be addressed as will the randomized controlled trials associated with that. The station of topical therapy will be addressed, along with innovative legal transfer mechanisms such as iontophersis and electromotive therapy. The literature will be reviewed with regards to lithotripsy, and the place of combined medical therapy alike reviewed.


A patient becomes a surgical candidate when he has stable and quiescent disease and that usually is a time that is greater than a year from onslaught of symptoms. The misshapenness should be stable for at least 3-6 months. The patient should be erectile pain sensation free. These patients expect detailed judgment of their erectile subprogram, and it is imperative that a true informed consent be conducted with the patient. Surgical management options admit the flexure or corporoplasty techniques. I will revue my techniques for these procedures. The place of excision or incision with grafting will be demonstrated and reviewed and the place of prosthetic placement likewise will be reviewed. As mentioned, surgery for Peyronie's disease must be highly personalised, and in most cases, lecturers focal point on those procedures that they take had the best success with.


Presented by: Gerald H. Jordan, MD, FACS, FAAP, at the Masters in Urology Meeting - July 31, 2008 - August 2, 2008, Elbow Beach Resort, Bermuda

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Wednesday 6 August 2008

Paradox and Seba

Paradox and Seba   
Artist: Paradox and Seba

   Genre(s): 
Drum & Bass
   



Discography:


Freak (FREAK014)   
 Freak (FREAK014)

   Year: 2005   
Tracks: 2